David, I was never troubled with vibration on my Ducati V2S. I did at first notice some vibes through the handlebars, but I suppose what you notice on any new bike can depend on what you were riding before - a series of BMWs in my case. I did find that the V2S engine was designed to be quite “sporty”, especially at higher revs, and at those speeds there was a certain buzz. But nothing that I would suggest would put off a likely buyer.